Click Here to return To Results

 

Avoiding False Positive Diagnoses of Motor Neuron Disease:Lessons from the Scottish Motor Neuron Disease Register JNNP 60:147-151, Davenport,R.J.,et al, 1996 See this aricle in Pubmed Article Abstract Seven of these patients were labeled as"MND plus"syndromes and may represent a distinct subset of MND.The remaining 46 patients had an alternative diagnosis made(false positive group),accounting for 8%of the total.In half of these cases,potentially beneficial therapies are available.The predominant reasons which lead to a diagnostic revision were:failure of symptom progression,development of atypical clinical features for MND and investigation results.Patients with MND should undergo thorough and relevant investigations at presentation with the emphasis on neuroradiological imaging and neurophysiology;all patients should be followed up by an experienced neurologist,particularly those in whom symptoms and signs are restricted to either the bulbar or spinal muscles;failure of symptoms progression or development of atypical features should lead to an early reassessment;finally,patients should be informed of the diagnosis only when it is secure.

Related Tags

(click to filter results - removes previous filter) amyotrophic lateral sclerosis amyotrophic lateral sclerosis,differential diagnosis amyotrophic lateral sclerosis,misdiagnosis misdiagnosis motor neuron disease neurologic disease,diagnoses of

Click Here to return To Results